First provide a summary of the paper, and then address the following criteria: Quality, clarity, originality and significance. The paper introduces the case of estimating a sparse chain graphical model in a high-dimensional data setting. It estimates a sparse autoregressive and sparse covariance structure. The method considers one-and multi-levels chain graphical models. The examples and applications are interesting.

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In this paper, we address the problem of learning the structure of Gaussian chain graph models in a high-dimensional space. Chain graph models are generalizations of undirected and directed graphical models that contain a mixed set of directed and undirected edges. While the problem of sparse structure learning has been studied extensively for Gaussian graphical models and more recently for conditional Gaussian graphical models (CGGMs), there has been little previous work on the structure recovery of Gaussian chain graph models. We consider linear regression models and a re-parameterization of the linear regression models using CGGMs as building blocks of chain graph models. We argue that when the goal is to recover model structures, there are many advantages of using CGGMs as chain component models over linear regression models, including convexity of the optimization problem, computational efficiency, recovery of structured sparsity, and ability to leverage the model structure for semi-supervised learning. We demonstrate our approach on simulated and genomic datasets.

Bayesian networks are a popular representation of asymmetric (for example causal) relationships between random variables. Markov random fields (MRFs) are a complementary model of symmetric relationships used in computer vision, spatial modeling, and social and gene expression networks. A chain graph model under the Lauritzen-Wermuth-Frydenberg interpretation (hereafter a chain graph model) generalizes both Bayesian networks and MRFs, and can represent asymmetric and symmetric relationships together.As in other graphical models, the set of marginals from distributions in a chain graph model induced by the presence of hidden variables forms a complex model. One recent approach to the study of marginal graphical models is to consider a well-behaved supermodel. Such a supermodel of marginals of Bayesian networks, defined only by conditional independences, and termed the ordinary Markov model, was studied at length in (Evans and Richardson, 2014).In this paper, we show that special mixed graphs which we call segregated graphs can be associated, via a Markov property, with supermodels of a marginal of chain graphs defined only by conditional independences.

In this paper, we address the problem of learning the structure of Gaussian chain graph models in a high-dimensional space. Chain graph models are generalizations of undirected and directed graphical models that contain a mixed set of directed and undirected edges. While the problem of sparse structure learning has been studied extensively for Gaussian graphical models and more recently for conditional Gaussian graphical models (CGGMs), there has been little previous work on the structure recovery of Gaussian chain graph models. We consider linear regression models and a re-parameterization of the linear regression models using CGGMs as building blocks of chain graph models. We argue that when the goal is to recover model structures, there are many advantages of using CGGMs as chain component models over linear regression models, including convexity of the optimization problem, computational efficiency, recovery of structured sparsity, and ability to leverage the model structure for semi-supervised learning. We demonstrate our approach on simulated and genomic datasets.

Bayesian networks are a popular representation of asymmetric (for example causal) relationships between random variables. Markov random fields (MRFs) are a complementary model of symmetric relationships used in computer vision, spatial modeling, and social and gene expression networks. A chain graph model under the Lauritzen-Wermuth-Frydenberg interpretation (hereafter a chain graph model) generalizes both Bayesian networks and MRFs, and can represent asymmetric and symmetric relationships together. As in other graphical models, the set of marginals from distributions in a chain graph model induced by the presence of hidden variables forms a complex model. One recent approach to the study of marginal graphical models is to consider a well-behaved supermodel.

We study identifiability of Andersson-Madigan-Perlman (AMP) chain graph models, which are a common generalization of linear structural equation models and Gaussian graphical models. AMP models are described by DAGs on chain components which themselves are undirected graphs. For a known chain component decomposition, we show that the DAG on the chain components is identifiable if the determinants of the residual covariance matrices of the chain components are monotone non-decreasing in topological order. This condition extends the equal variance identifiability criterion for Bayes nets, and it can be generalized from determinants to any super-additive function on positive semidefinite matrices. When the component decomposition is unknown, we describe conditions that allow recovery of the full structure using a polynomial time algorithm based on submodular function minimization. We also conduct experiments comparing our algorithm's performance against existing baselines.

This paper provides a graphical characterization of Markov blankets in chain graphs (CGs) under the Lauritzen-Wermuth-Frydenberg (LWF) interpretation. The characterization is different from the well-known one for Bayesian networks and generalizes it. We provide a novel scalable and sound algorithm for Markov blanket discovery in LWF CGs and prove that the Grow-Shrink algorithm, the IAMB algorithm, and its variants are still correct for Markov blanket discovery in LWF CGs under the same assumptions as for Bayesian networks. We provide a sound and scalable constraint-based framework for learning the structure of LWF CGs from faithful causally sufficient data and prove its correctness when the Markov blanket discovery algorithms in this paper are used. Our proposed algorithms compare positively/competitively against the state-of-the-art LCD (Learn Chain graphs via Decomposition) algorithm, depending on the algorithm that is used for Markov blanket discovery. Our proposed algorithms make a broad range of inference/learning problems computationally tractable and more reliable because they exploit locality.

Bayesian networks are a popular representation of asymmetric (for example causal) relationships between random variables. Markov random fields (MRFs) are a complementary model of symmetric relationships used in computer vision, spatial modeling, and social and gene expression networks. A chain graph model under the Lauritzen-Wermuth-Frydenberg interpretation (hereafter a chain graph model) generalizes both Bayesian networks and MRFs, and can represent asymmetric and symmetric relationships together.As in other graphical models, the set of marginals from distributions in a chain graph model induced by the presence of hidden variables forms a complex model. One recent approach to the study of marginal graphical models is to consider a well-behaved supermodel. Such a supermodel of marginals of Bayesian networks, defined only by conditional independences, and termed the ordinary Markov model, was studied at length in (Evans and Richardson, 2014).In this paper, we show that special mixed graphs which we call segregated graphs can be associated, via a Markov property, with supermodels of a marginal of chain graphs defined only by conditional independences.

Bayesian networks are a popular representation of asymmetric (for example causal) relationships between random variables. Markov random fields (MRFs) are a complementary model of symmetric relationships used in computer vision, spatial modeling, and social and gene expression networks. A chain graph model under the Lauritzen-Wermuth-Frydenberg interpretation (hereafter a chain graph model) generalizes both Bayesian networks and MRFs, and can represent asymmetric and symmetric relationships together.As in other graphical models, the set of marginals from distributions in a chain graph model induced by the presence of hidden variables forms a complex model. One recent approach to the study of marginal graphical models is to consider a well-behaved supermodel. Such a supermodel of marginals of Bayesian networks, defined only by conditional independences, and termed the ordinary Markov model, was studied at length in (Evans and Richardson, 2014).In this paper, we show that special mixed graphs which we call segregated graphs can be associated, via a Markov property, with supermodels of a marginal of chain graphs defined only by conditional independences. Special features of segregated graphs imply the existence of a very natural factorization for these supermodels, and imply many existing results on the chain graph model, and ordinary Markov model carry over. Our results suggest that segregated graphs define an analogue of the ordinary Markov model for marginals of chain graph models.